Although genetics plays an important role in the transmission of lupus, it is not a determining factor. Just because someone in your family has it doesn’t mean you will, too. Its appearance is favored by other factors such as the environment, stress or hormones, including estrogen, which is largely responsible for the disease in women.
Lupus usually affects people between the ages of 15 and 44, which is the period when women are most sexually active and fertile. It also appears in people between the ages of 70 and 80.